Synthetic Biology
based on standard parts
iGEM 2015 Team Information
Team Name: | Fudan |
Team Code: | 177715 |
Schools: | Fudan University
Shanghai, China
www.fudan.edu.cn |
Kind: | Collegiate | Application Date: 2015-03-26 |
Division: | iGEM | Acceptance Date: 2015-04-14 08:35:55 |
Region: | Asia |
Country: | CHINA |
Section: | Undergraduate
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Your iGEM 2015 team application was accepted by iGEM Headquarters on 2015-04-14 08:35:55.
However, your registration is not complete until your team registration fee is paid. See how to pay your fees below. |
Assigned Track: Foundational Advance
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Cyclize it!
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Circular RNA is a type of RNA which forms a covalently closed loop. They are known to be resistant to RNases due to lack of ends, and thus have extraordinary stability. Recently several naturally generated circular RNAs are found to act as miRNA sponges, and they are a new type of tumor suppressors, because the miRNA the regulate are linked to cell proliferation and cancer. Our team has designed fusion proteins to promote miRNA sponge circularization, which can make miRNA sponges more stable and potent. Our circular RNA sponges can be used as a new tool to regulate gene expression, and in the future, it may be used as a new type of anti-cancer drug.
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This range of part numbers has been assigned to your team for use during the summer: BBa_K1777000 to BBa_K1777999
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