Synthetic Biology
based on standard parts
iGEM 2022 Team Information
Team Name: | LINKS_China |
Team Code: | 427365 |
Schools: | LINKS Academy
Shenzhen, Guangdong, China
https://www.links-academy.net/ |
Kind: | Commercial | Application Date: 2022-04-13 |
Division: | iGEM | Acceptance Date: 2022-06-15 11:25:25 |
Region: | Asia |
Country: | China |
Section: | High_School
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Welcome to iGEM 2022 ! Your iGEM 2022 team application was accepted by iGEM Headquarters on 2022-06-15 11:25:25. |
Assigned Track: High School
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UV-PRISMA: UltraViolet radiation Protection and skin Repairing by Innovative Sunscreen with Mycosporine-like Amino acids
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UV-radiation damages our skin, causing sunburn, inflammation and skin aging. Mycosporine-like amino acids (MAAs) are natural products produced by various marine organisms such as cyanobacteria and algae, able to absorb UV radiation. However, the low rate of MAA production limits the potential of commercializing MAAs as sunscreen ingredient.
This year, LINKS_China engineered Saccharomyces cerevisiae to produce three MAAs—shinorine, porphyra-334 and palythine—and another UV-absorbing molecule, gadusol. We incorporated enzymes from Nostoc punctiforme, Nostoc linckia and Actinosynnema mirum to structure the optimal pathway, and introduced the xylose metabolism pathway to increase yield. These yeast products has successfully absorbed UV radiation, covering most UVA and UVB rays. For skin repairing, we introduced superoxide dismutase and catalase to remove reactive oxidative species produced in the skin.
UV-PRISMA, our MAA-based sunscreen product, will bring a healthier, gentler, and more environmentally friendly way of UV protection.
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Pending Membership Applications | | |
This range of part numbers has been assigned to your team for use during the summer: BBa_K4273000 to BBa_K4273999
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