Synthetic Biology

based on standard parts

iGEM 2023 Team Information

Team Name: LINKS-China
Team Code:480594
Schools:
Shenzhen College of International Education; Shenzhen, Guangdong Province, PRC ; https://www.scie.com.cn/
BASIS International School Shenzhen; Shenzhen, Guangdong Province, PRC ; https://bisz.basischina.com/#/home?lang=en
BASIS International School Park Lane Harbour; Huizhou, Guangdong Province, PRC ; https://biph.basischina.com/#/home?lang=en
Tsinglan School; Dongguan, Guangdong Province, PRC 
Kind:CommercialApplication Date:  2023-04-24
Division:iGEMAcceptance Date: 2023-05-25 06:12:11
Region:Asia
Country:China
Section:High_School

Team Registration 2023
Welcome to iGEM 2023 ! Your iGEM 2023 team application was accepted by iGEM Headquarters on 2023-05-25 06:12:11.
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Safety
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TrackMore...
Assigned Track: High School

Title and AbstractMore...
Aroma Anchor
Ambergris and Sandalwood Oil are both well-known fragrance fixatives since centuries before. However, people hunted and killed sperm whales to obtain ambergris and the growing of sandalwood is highly time and cost consuming. LINKS-China 2023 aims to produce ambrein and santalol, the major components of the fixatives using yeast cell-factory. By engineering S.cerevisiae, we optimized the MVA pathways by over expressing tHMG1 and IDI1. Then, we constructed the pathway of santalene production by expressing ClSS and its mutant. After that, we inserted CYP736A167 and SaCPR2 to convert santalene into santalol. We also constructed a pathway producing ambrein by inserting two different integrations. In the end the yeasts are able to produce 24.23 mg/L of santalene and 40.65 mg/L of santalol, and we have found the most suitable integration for ambrein production. We wrote market analysis to plan the future development of our project. We expect that in the future, LINKS-China will be able to provide society with an economical and high-quality fragrance fixatives.

Team Roster
Primary PI   [Required]
diolatcgBoxiang Wang
Secondary PI   [Recommended] More...
suzansqQing Liang
Instructors
GarmenJiawen Chen
Student Leaders
YolandaaaaaYuhan Gan
AndyXiaoXingyu Xiao
LTSLTSLTSTianshu Liu
KeliJunxin Zhang
Student Members
sandrae9Sandra Oseakhumen Emhenya
AndersonYangYang Yi
IreneXieYuhan Xie
Mega-MangoYUXUAN CHEN
WilliamZhaoTianyin Zhao
Angel_123Fangyu Zhan
BelleYanYAN ZIYU
selinaluMing Shu Lu
SophieGongRongyue Gong
Eln-ywYunwen Ma
bellaliZijia Li
Mr_DYeYao Du
HanaRinDingran Hong
Tianna_WuYutian Wu
elwaieksYaxuan Liu
AlexChen002Xiaoyong Chen
FGGong Yuxin
yeeheejunxing zhu
Meando_XuMingduo Xu
ArendelleTanTan Yawen
lrj-077Tinac Xing
CatherineeeYitang Wang
Advisors
StephenYeQidang Ye
galaxydud3Ziteng Feng
SUHONGHAOSu Honghao

This range of part numbers has been assigned to your team for use during the summer: BBa_K4805000 to BBa_K4805999